The HiSeq X Five and Ten Systems have been discontinued. We will continue to provide full support of the instruments and supply the reagents through March 31, 2024. To find an alternative instrument, we recommend using the Sequencing Platform Comparison Tool.
HiSeq X
Human WGS with the HiSeq X Five System
The HiSeq X Five System enables WGS at a cost and scale appropriate for large genome centers, and offers a scalable path to $1000 human genome capacity. With a lower initial capital investment, the HiSeq X Five System consists of 5 individual HiSeq X instruments, which together can sequence over 9000 genomes per year.
System Specifications
1.6–1.8 Tb
output range
5.3–6 billion
reads per run
2 × 150 bp
max read lengthTrade in your HiSeq instrument for more discovery power.
If you currently own a HiSeq 2500, HiSeq 3000/4000, or HiSeq X, you may be eligible to trade in your existing instrument for a new NovaSeq 6000 System. This program is available for a limited time only. Terms and conditions apply. Fill out the form below to contact a sales representative to see if you are eligible.
Customer Stories
Our Lives in Data Exhibit at the London Science Museum
The Illumina HiSeq X instrument will be on display as an example of how sequencing technology is playing a crucial part in helping amass the data in the 100,000 Genomes Project that will allow scientists to do pioneering research.
View VideoCost-Effective Sequencing Enables Researchers to Scale Cancer Study
Garvan researchers use the HiSeq System to identify cancer-associated variants in the germline.
Read articleUnmasking Autoimmune Diseases Using Genomics
Researchers are performing WGS and WES to identify variants associated with lupus and other autoimmune disorders.
Read article